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tirsdag 5. februar 2013

Updated Europe analysis

New updated Europe regional analysis. I have removed the Orcadians as they give odd clusterings in the PCA because of relatedness, but one British group who have in earlier analysis clustered with them work fine as stand-ins. In the regional analysis more substructure is revealed. Caucasus not included.

As we can see for the Fennoscandians much is as before, but the addition of more continental Europeans have revealed more structure. We see that the 2 new Germans have clustered the dispora individuals Ux who have at least partly German and English ancestry into one group close to one group of the British, also containing a few French and one British.

The 1 new Austrian appears to cluster closest with the Romanians. We see 3 of the 4 new Polish cluster with the Ukrainians and Belorussian cluster while the last cluster with the Lithuanians. Most of the new Russians appears to cluster together with the 2 Estonians already in the project. However note the Estonians appears to pull away from the Russian cluster on the main PCA D1-D2 plot.


CC Europe Aggregated
CC Euro Populations

CC Euro Raw

(PCA plots in order D1-Dx+)




12 kommentarer:

  1. Please note that Romanian3 and Romanian7 appear to be Romanian Rom-people as they in the CCWorld cluster with different tribes in Pakistan.

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  2. Interesting. But what is with the two groups of Finns? Shouldn't they be grouped the other way around? I don't know, I might be too tired to think straight...

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  3. Suvi: Depending if we have a world analysis or local analysis the grouping would differ because smaller differences are ignored in the world analysis than in the local analysis. In this analysis Finns basically divide into West-Finns (Finns2) and East-Finns (Finns1). In the local Fennoscandina analysis where even smaller differences is seen the grouping of Finns is even more divided.

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  4. OK, makes sense, but I thought that the Saami individuals would get grouped with Finns1 instead of Finns2. Anyway, my DNA Tribes update showed ~10% more on the Slavic-Baltic component compared to the average Finn. Should I be able to see that here?

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  5. Suvi: First I you want to infer finer substructures between Fennoscandians you should use the local Fennoscandian analysis. I agree that this placement at first looks weird as if you see the aggregated heatmap the Saamis appear closer to East-Finns than West-Finns. So it must be something else that made the tree like this in this instance.

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  6. Suvi: I do not see anything that make you deviate much from Finns but on PCA plots you tend to go strong towards Scandinavians.

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  7. Thanks! According to 23andMe, I'm 76.3% Finnish and 7.1% Scandinavian. Not sure how accurate that thing is... But is it the Scandinavian component that caused them to be grouped like that?

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  8. Suvi: I do not know DNATribes methods but if they are based on ADMIXTURE based analysis with independent SNP they are not based on state-of-the-art analysis software like Chromopainter/Finestructure that is haplotype based.

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  9. Well, it was the SNP test. They do offer an STR one as well.

    All these different tests give very different answers. Some say that I'm more Western European, others say that I'm more Eastern European. The Eurogenes Jtest Oracle on Gedmatch says: "50% East_Finnish +50% North_Swedish @ 4.599". 50% North Swedish, eh? But does it mean that the variance is 5%? *shrug* (kit M065536 on Gedmatch)

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  10. Suvi: Personnally I dint trust these calculators. Chromopainter/Finestructure unfortunantly dont give you the exact percentages, having percentages is of course much easier to understand than these heatmaps.

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  11. Is it a bit weird to use Saamic and East Finnish components flattening the whole European picture on almost all plots? This definitely leads to the compression of all other European groups. It is possible to take one of the biggest diviation overweighting it and selecting other dimension containing smallest deviation among Europeans.

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  12. Mikej2: The project goals is about the genetic origin of Fennoscandians so begin leaving out Saamis and Finns would take the project goals astray.

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